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• “In most developed countries, purchasing from brick-and-mortar pharmacies is generally safe. Any stories you hear about counterfeit medications become interesting and newsworthy because they are not the norm.”
• We set out to describe the variation in prescribing of pregabalin and branded Lyrica across the country and over time; to determine the impact of the NHS England instruction to GPs; and to model the additional costs to the NHS attributable to various legal judgments.
• All respondents combined pregabalin with alcohol, and most respondents combined pregabalin with other central nervous system depressants and opioids.

The agency relies on patients, providers, and pharmacies to voluntarily share information about counterfeit or suspected counterfeit medication. This imports openly accessible prescribing data from the monthly files published by the NHS Business Services Authority.2 These contain data on cost and volume prescribed for each drug, dose and preparation, for each month, for each English general practice. From this dataset we extracted data on all prescriptions dispensed between April 2013 and July 2016 for pregabalin capsules of any form.

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